EDUCATION
Research Article on the Effect of siRNA-Mediated Interference on CDC14A Expression in Gastric Cancer MKN-45 Cells
By TEAM CIRCULAR EXPRESS • 10 Oct 2026
👁 13 views
• This research article investigates the role of CDC14A phosphatase in gastric cancer progression using MKN-45 cell lines.
• Bioinformatics analysis identified 250 differentially expressed genes linked to cell adhesion and metabolic pathways.
• Functional assays demonstrate that silencing CDC14A triggers G0/G1 cell cycle arrest and inhibits cell growth, while overexpression promotes colony formation.
• Bioinformatics analysis identified 250 differentially expressed genes linked to cell adhesion and metabolic pathways.
• Functional assays demonstrate that silencing CDC14A triggers G0/G1 cell cycle arrest and inhibits cell growth, while overexpression promotes colony formation.
purpose of issuance
To investigate the regulatory role of CDC14A in gastric cancer tumorigenesis and its potential as a therapeutic target.
Most Important Details
The study confirms that CDC14A modulates cell cycle progression and proliferative behavior in gastric cancer cells. Downregulation of CDC14A inhibits cell growth and colony formation, while overexpression enhances it, suggesting CDC14A as a viable marker for precision therapy.
Location of Work
Peking University Cancer Hospital (Inner Mongolia Campus), Hohhot, China
🔒 Document — view only
Regards, Circular Express
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Research Article on the Effect of siRNA-Mediated Interference on CDC14A Expression in Gastric Cancer MKN-45 Cells
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EDUCATION
Research Article on the Effect of siRNA-Mediated Interference on CDC14A Expression in Gastric Cancer MKN-45 Cells
By TEAM CIRCULAR EXPRESS • 10 Oct 2026
👁 13 views
• This research article investigates the role of CDC14A phosphatase in gastric cancer progression using MKN-45 cell lines.
• Bioinformatics analysis identified 250 differentially expressed genes linked to cell adhesion and metabolic pathways.
• Functional assays demonstrate that silencing CDC14A triggers G0/G1 cell cycle arrest and inhibits cell growth, while overexpression promotes colony formation.
• Bioinformatics analysis identified 250 differentially expressed genes linked to cell adhesion and metabolic pathways.
• Functional assays demonstrate that silencing CDC14A triggers G0/G1 cell cycle arrest and inhibits cell growth, while overexpression promotes colony formation.
purpose of issuance
To investigate the regulatory role of CDC14A in gastric cancer tumorigenesis and its potential as a therapeutic target.
Most Important Details
The study confirms that CDC14A modulates cell cycle progression and proliferative behavior in gastric cancer cells. Downregulation of CDC14A inhibits cell growth and colony formation, while overexpression enhances it, suggesting CDC14A as a viable marker for precision therapy.
Location of Work
Peking University Cancer Hospital (Inner Mongolia Campus), Hohhot, China
🔒 Document — view only
Regards, Circular Express
Similar Circulars
office orders regarding appointment of Director, PDDUCSVE and Deputy Director, PDDUCSVE, MDU, Rohtak
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Syllabi and Scheme of Examinations for Multidisciplinary Courses in Sanskrit, Maharshi Dayanand University Rohtak
#Education#Examination
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#College/University#Education#Haryana
Syllabi and Scheme of Examinations for B.A. Sanskrit Single Major Program, Maharshi Dayanand University Rohtak
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