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Proteomic Analysis of Uranium Bioaccumulation and Toxicity in Aeromonas Bacterium by Current Science

By TEAM CIRCULAR EXPRESS • 10 Oct 2026
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• This research article investigates how Aeromonas bacteria respond to uranium exposure under alkaline conditions.
• Using MALDI-TOF and 2D-gel electrophoresis, the study identifies 44 differentially regulated proteins.
• Findings show up-regulation of proteins involved in energy metabolism, DNA repair, and ion transport, alongside down-regulation of transcription and translation processes as a survival mechanism.
Research Topic
Uranium bioaccumulation and toxicity in Aeromonas bacterium
Methodology
2D-gel electrophoresis and MALDI-TOF mass spectrometry
Key Findings
Up-regulation of 34 proteins and down-regulation of 12 proteins in response to uranium stress
Issuing Body
Current Science
Authors
Uday Kumar Banala, Shunmugiah Karutha Pandian, Toleti Subba Rao
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